Duke's Seth Curry drives past Keith Appling of Michigan State in the second half during the Midwest Region semifinal in Indianapolis on Friday. The Dukes will be underdogs against Louisville in the final on Sunday. (Photo: Andy Lyons Getty Images) INDIANAPOLIS – In the last 22 years since Mike Krzyzewski won his first national title, Duke has brought all kinds of teams to the NCAA tournament. There have been true powerhouses filled with future pros and rosters that were limited in various ways; overachievers, underachievers and teams that probably wouldn't have been considered contenders in the first place if their jerseys didn't read Duke. But no matter how good or bad a team Krzyzewski had, the thing that could almost never be said about Duke is that they are underdogs in an NCAA tournament game. Whenever Duke's season ends without a championship, it is practically a national event. So it will be a bit strange at Lucas Oil Stadium on Sunday watching something rarely conceived in the modern history of college basketball: A Duke team that really isn't supposed to beat No. 1 seed Louisville in the Midwest Regional final. NCAA TOURNAMENT: Full bracket, scores SCHEDULE: Elite Eight TV schedule, info "We know going into every game that we're a target," Krzyzewski said. "And we'll be a target tomorrow." The arc of this Duke season, however, is unusual in Krzyzewski's career. Barely considered in the preseason as a team that could win the national title, Duke had the look of dominance in early December, collecting huge early non-conference wins until its momentum was interrupted by injuries. Then after getting healthy again in early March with the return of forward Ryan Kelly, who missed 13 games with a foot injury, the Blue Devils were stamped as favorites once again to win the whole thing. Until, of course, Duke lost to Maryland in the ACC tournament, relegating them to a No. 2 seed in the same region as the overall No. 1. Since then, there hasn't been much talk about Duke; at least not until it put on a defensive clinic against Michigan State in the Sweet 16, winning 71-61. In that game, the Blue Devils showed clearly they are capable of winning the tournament. Still, this is an atypical situation for Duke. In their last nine NCAA tournaments (except for the 2010 championship team), the Blue Devils have been eliminated by a lower-seeded team. PITINO-COACH K: Two great coaches on one great game CURRY: Seth in a different situation than his brother Thus, this is the first time since 2003, when it lost as a No. 3 seed to No. 2 seed Kansas in the Sweet 16, that Duke goes into an NCAA tournament game as an underdog. And that's a hard way to think about Krzyzewski's program, given all of the history and privileges that go along with its status. "Throughout the whole year and this tournament we've been picked against a lot," guard Seth Curry said. "That's nothing new. At the same time, we're Duke." And that's the part where this entire season, and particularly this tournament run, seems like an outlier. PHOTOS: Best shots from the Elite Eight Story Highlights
Duke in unusual position against top-seeded Louisville
Wichita State head coach Gregg Marshall celebrates cutting down the net after beating Ohio State 70-66 in the West Regional final to advance to the Final Four. Robert Hanashiro, USA TODAY
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Wichita State's Carl Hall, left, celebrates winning the West Regional final 70-66 over Ohio State. Richard Mackson, USA TODAY Sports
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Wichita State head coach Gregg Marshall hoists the West Regional trophy after the Shockers topped second-seeded Ohio State 70-66 at the Staples Center in Los Angeles. Jayne Kamin-Oncea, USA TODAY Sports
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Wichita State players celebrate after topping Ohio State 70-66 at the Staples Center in Los Angeles to advance to the Final Four. Jayne Kamin-Oncea, USA TODAY Sports
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Wichita State's Demetric Williams, right, celebrates after topping Ohio State 70-66 in the West Regional final to advance to the Final Four. Jayne Kamin-Oncea, USA TODAY Sports
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Wichita State players celebrate on the bench in the second half of the West Regional final vs. Ohio State. The Shockers won 70-66 to advance to the Final Four. Jayne Kamin-Oncea, USA TODAY Sports
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Ohio State guard Aaron Craft is defended by Carl Hall (22) and Cleanthony Early in the second half of the West Regional final at the Staples Center in Los Angeles. Richard Mackson, USA TODAY Sports
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Ohio State's Aaron Craft shakes hands with teammate Shannon Scott early in the second half of the West Regional final at the Staples Center in Los Angeles. Robert Hanashiro, USA TODAY
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Wichita State's Carl Hall is elbowed in the chin by Ohio State's Deshaun Thomas as he attempted a shot in the second half. Richard Mackson, USA TODAY Sports
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Ohio State head coach Thad Matta reacts during the first half. Wichita State led 35-22 at the break. Richard Mackson, USA TODAY Sports
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Ohio State's Aaron Craft and Wichita State's Cleanthony Early look to get a handle on a loose ball in the first half. Richard Mackson, USA TODAY Sports
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Wichita State's Carl Hall shoots over Ohio State's Deshaun Thomas. Jayne Kamin-Oncea, USA TODAY Sports
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Wichita State's Malcolm Armstead tries to shoot on Ohio State's Amir Williams in the first half. Richard Mackson, USA TODAY Sports
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Ohio State's Deshaun Thomas (1) and center Amir Williams (23) defend against Wichita State's Carl Hall in the first half of the West Regional final at the Staples Center in Los Angeles. Richard Mackson, USA TODAY Sports
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Wichita State's Malcolm Armstead tries to shoot over Ohio State forward Deshaun Thomas in the first half. Richard Mackson, USA TODAY Sports
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Wichita State's Ron Baker goes up for a layup against Ohio State's Evan Ravenel in the first half of their Elite Eight matchup in Los Angeles. Jayne Kamin-Oncea, USA TODAY Sports
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Wichita State's Malcolm Armstead dribbles the ball in front of Ohio State forward Evan Ravenel (30) and Shockers forward Carl Hall (22) in the first half. Robert Hanashiro, USA TODAY
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Ohio State's Deshaun Thomas shoots against Wichita State's Ehimen Orukpe in the first half of the West Regional final at the Staples Center in Los Angeles. Robert Hanashiro, USA TODAY
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Wichita State's Tekele Cotton (32) and Ohio State's Aaron Craft go after a loose ball in the first half. Richard Mackson, USA TODAY Sports
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Ohio State's Amir Williams gets the opening tipoff against Wichita State's Cleanthony Early to start the West Regional final in Los Angeles. Jayne Kamin-Oncea, USA TODAY Sports
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Syracuse coach Jim Boeheim cuts down the net after the Orange defeated Marquette 55-39 to win the East Regional and advance to the program's first Final Four since 2003. Bob Donnan, USA TODAY Sports
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Syracuse's C.J. Fair celebrates with teammates after defeating Marquette 55-39 in Washington to advance to the Final Four. Bob Donnan, USA TODAY Sports
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Syracuse's Rakeem Christmas celebrates with fans after defeating Marquette in the East Regional final. Geoff Burke, USA TODAY Sports
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Syracuse players hold up the East Regional trophy after defeating Marquette 55-39 at the Verizon Center in Washington. Geoff Burke, USA TODAY Sports
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Jim Boeheim holds the East Regional trophy after the 55-39 win over Marquette. Geoff Burke, USA TODAY Sports
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Syracuse's C.J. Fair, left, celebrates with Michael Carter-Williams after topping Marquette 55-39 in the Elite Eight, earning a trip to the Final Four. Bob Donnan, USA TODAY Sports
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Syracuse players celebrate after beating Marquette 55-39 in the East Regional final in Washington to earn the program's first Final Four berth since 2003. Bob Donnan, USA TODAY Sports
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East Regional final (Washington): Syracuse's Michael Carter-Williams (1) and forward James Southerland (back) celebrate in the final seconds of the Orange's 55-39 win. Geoff Burke, USA TODAY Sports